When in liquid form, the somatropin molecules are very fragile. They easily get destroyed by heat (even room temperatures) and vigorous shaking. Some precautions are necessary - do not inject the water directly into the powder with force, do not drop or shake a reconstituted vial, do not freeze it and do not leave it out of the refrigerator for longer than a few minutes. Keep the freeze dried (lyophilized) growth hormone vials refrigerated as well.
Human growth hormone can be reconstituted with several types of water, including sterile bacteriostatic water (0.9% sodium chloride), normal saline (0.9% NaCl) or plain sterile water for injection. Any will work, but if possible the plain sterile water should be used.
Although HGH can be mixed and injected with any type and size of syringe, the Insulin type syringes are the most suitable. If possible get the ones with 100 markings on the side. It will make it easier to properly determine the dosage of HGH.
3. HGH mixing (reconstitution) instruction:
Remove the plastic cap from the top of the vial and clean the rubber with a medical alcohol pad/swab. Take and insulin syringe and pull 1 ml of water (100 markings) into it. Note: regardless of how much water you use (be it 1ml or 2ml) the mixture still has the same overall strength. Water is just a transport method for the HGH. If you used double amount of water when reconstituting the HGH, you would have to use double amount of mixture when injecting yourself to get the same dose. People usually use 1ml because it fits fully into a standard insulin type syringe.
You now have 1ml of water in the syringe. Push the needle through the rubber cap of the vial, but position it sideways so that the water will slide down the inside wall of the vial. Do not inject directly into the powder with force, rather let the water slide out slowly.
Majority of the white powder will dissolve within seconds, but there will be some lumps left over. Do not shake the vial in an attempt to get them to dissolve. If you are in a hurry, you can gently roll the vial between your fingers. If you do this for a few minutes all of the powder will dissolve. Alternatively you can let the vial sit in the refrigerator for 15 - 30 minutes. By that time the somatropin will dissolve completely.
Before pulling the liquid HGH into the insulin syringe, give the vial a few turns between your fingers to gently mix the solution. The HGH vials are under vacuum (negative air pressure) which makes it harder to pull the liquid out. To relieve the vacuum inject a full syringe of air into the top of the vial (do not make the liquid bubble).
Some people use a new syringe for each injection, others pull the entire content of the HGH vial into the syringe and reuse it several times until it's empty. The choice is yours.
4. HGH Dosage:
If somatropin was prescribed to you by a doctor follow his dosage instructions. If you are self prescribing/administering the general dosage guidelines are as follows:
- 2 IU per day is used for anti aging purposes. You can inject it any time of the day or a full or empty stomach - it does not matter. It might be the most beneficial to take it in the morning, or at least a few hours before bedtime because the body releases its own endogenous growth hormone after a person falls asleep. Injecting before bedtime might reduce the body's own release - robbing you of a free bonus dose.
- 4 IU per day is usually used by athletes for bodybuilding, fat loss and general fitness. Some people take 6IU per day, however the higher the dose the more annoying the side effects can be. Carpal tunnel syndrome being the side effect which usually forces the athlete to lower the dose or pause the cycle for 2 - 3 weeks until the carpal disappears. It is preferred to spread the daily dose into multiple injections throughout the day. For example 2 IU in the morning and 2 IU in late afternoon.
- 8 to 16 IU per day is used to speed up recovery after severe burns or injuries. This is a pretty high dose and it should not be continued for more than a few weeks. The carpal tunnel syndrome will probably bother the user, but in the name of faster recovery some discomfort may be tolerable.
Personally tailored, self determined HGH dose
Anything between 2 and 4 IU per day is fine. Each person can determine his body's own preferred dosage. When you get to the carpal tunnel syndrome - that's your limit. For prolonged use it is ok to barely feel the carpal - that's how you know the HGH is working while it doesn't bother you too much. For short periods of time some athletes chose to ignore even the strongly felt syndrome and keep on going until their goals are achieved.
Raised growth hormone levels also make the body use it's thyroid hormone at a heightened pace. While using HGH It is a good idea to periodically check all your hormone levels to make sure everything is ok. If the thyroid levels are too low it might be time to lower the HGH dosage or pause the cycle for a while.
Warning: HGH has a direct effect on a person's blood sugar levels. If you have diabetes you might want to consult a professional before self administering growth hormone. While taking HGH your insulin levels might have to be adjusted. There would be a few days period of instability when first starting HGH, modifying the dosage or ending the HGH cycle. Diabetes patients might want to gradually build up to the desired HGH dose and at the end of the cycle also take 2-3 weeks to gradually phase out the HGH injections.
5. HGH injections:
Growth hormone can be injected intramuscularly (IM) into pretty much any muscle or subcutaneously (SQ) - under the skin in the stomach fat area. Injections above the belly button are usually less painful than the ones below the belly button. A different spot should be used for each injection (to avoid potentially producing dents in the body fat - as hgh is believed to promote localized fat reduction).
For SQ injections pinch the skin between your abs, fully insert the needle at a 30 - 45 degrees angle and inject your dose. For IM injections fully insert the needle into your shoulder or gluteus muscle and release the dose.
It is rumored that the SQ injections produce better effect due to the fact that HGH is more readily available from there. Personally I see no difference whether I inject IM or SQ. Injecting HGH intramuscularly is less unpleasant for me, so that's how I do it.
6. Starting or ending the HGH cycle
There are various internet forum misconceptions about the proper use of growth hormone. Some date back to the beginning of the internet and are still being repeated by people who "heard from a friend".
Some people think that growth hormone should be taken 5 days per week with 2 days pause in between. This is nonsense which only came about because back in the days HGH was prohibitively expensive and bodybuilders prolonged their cycles by skipping days and stretching it for as long as they could afford. The human body never pauses the production of it's endogenous growth hormone.
Some people believe that in beginning of the growth hormone cycle the desired dosage should be gradually built to and gradually phased out when the person is ready to end it. From my experience it makes no difference whether I phase in and out or start and stop with full dosage. On the other hand, I do get a few days of blood sugar instability (sudden hypoglycaemia) when I end my cycles. Within 2 days to 2 weeks after my cycle is complete I get sudden hunger attacks (blood sugar drops). I keep a candy bar handy for such episodes. It happens about 3 to 5 times in the 2 weeks period.